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New hope for tough leukemia: drug combo aims to clear resistant cancer

NCT ID NCT06660368

Recruiting now Disease control Sponsor: H. Lee Moffitt Cancer Center and Research Institute Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 24 times

Summary

This study tests whether adding venetoclax to standard chemotherapy (CLAG-M) helps people with relapsed or refractory acute myeloid leukemia (AML) achieve deeper remission and live longer without the cancer returning. About 52 adults aged 18–80 will be randomly assigned to receive either the combination or chemotherapy alone. The goal is to see if the combination is safe and more effective at clearing leukemia cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

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Conditions

Explore the condition pages connected to this study.

RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA (AML)