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Experimental combo for head and neck cancer shows promise but study halted early

NCT ID NCT05061420

Terminated Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This study tested a new drug called SAR444245 combined with other cancer treatments for people with advanced head and neck cancer that had spread or come back. The goal was to see if the combination could shrink tumors. The study was stopped early, so results are limited. It included adults aged 18 and older with certain types of head and neck cancer.

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Contacts and locations

Locations

  • City of Hope- Site Number : 8400007

    Duarte, California, 91010, United States

  • Investigational Site Number : 0320001

    Buenos Aires, 1012, Argentina

  • Investigational Site Number : 1240001

    Montreal, Quebec, H4A 3J1, Canada

  • Investigational Site Number : 1520001

    Santiago, Reg Metropolitana de Santiago, 8420383, Chile

  • Investigational Site Number : 1520002

    Temuco, 4800827, Chile

  • Investigational Site Number : 1520003

    Santiago, Reg Metropolitana de Santiago, 7500921, Chile

  • Investigational Site Number : 1520004

    Viña del Mar, Valparaiso, 2540488, Chile

  • Investigational Site Number : 1580003

    Tainan, 704, Taiwan

  • Investigational Site Number : 2500001

    Villejuif, 94800, France

  • Investigational Site Number : 2500002

    Strasbourg, 67033, France

  • Investigational Site Number : 2500003

    Bordeaux, 33075, France

  • Investigational Site Number : 2500006

    Paris, 75015, France

  • Investigational Site Number : 2500008

    Lyon, 69008, France

  • Investigational Site Number : 2760004

    Berlin, 12200, Germany

  • Investigational Site Number : 3800003

    Brescia, 25123, Italy

  • Investigational Site Number : 4100001

    Seoul, Seoul-teukbyeolsi, 06351, South Korea

  • Investigational Site Number : 4100002

    Seoul, Seoul-teukbyeolsi, 05505, South Korea

  • Investigational Site Number : 5280001

    Nijmegen, 6500 HB, Netherlands

  • Investigational Site Number : 5280002

    Amsterdam, 1066, Netherlands

  • Investigational Site Number : 7240001

    Barcelona, Barcelona [Barcelona], 08035, Spain

  • Investigational Site Number : 7240003

    Madrid, Madrid, Comunidad de, 28046, Spain

  • Investigational Site Number : 7240004

    Barcelona, Barcelona [Barcelona], 08036, Spain

  • Investigational Site Number : 7240005

    Madrid, Madrid, Comunidad de, 28040, Spain

  • Seattle Cancer Care Alliance Site Number : 8400006

    Seattle, Washington, 98115, United States

  • Thomas Jefferson University Hospital Site Number : 8400003

    Philadelphia, Pennsylvania, 19107, United States

  • University of Colorado- Site Number : 8400004

    Aurora, Colorado, 80045, United States

  • University of Michigan- Site Number : 8400008

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.

SQUAMOUS CELL CARCINOMA OF HEAD AND NECK