New drug combo aims to ease severe muscle weakness

NCT ID NCT07284420

First seen Jan 11, 2026 · Last updated May 07, 2026 · Updated 19 times

Summary

This study tests whether adding empasiprubart to the standard treatment efgartigimod can further improve symptoms in people with a specific type of generalized myasthenia gravis (gMG). About 70 adults who still have partial symptoms despite efgartigimod will receive the combination therapy. The main goals are to check safety and see if the add-on drug helps with daily activities like talking, chewing, and breathing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centrum Medyczne Neurologia Slaska

    RECRUITING

    Katowice, Silesian Voivodeship, 40-689, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dent Neurologic Institute - Amherst

    RECRUITING

    Amherst, New York, 14226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Erlanger Health System

    RECRUITING

    Chattanooga, Tennessee, 37403, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Regional Universitario de Malaga - Hospital General

    RECRUITING

    Málaga, Malaga, 29010, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MICS Centrum Medyczne Bydgoszcz

    RECRUITING

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Neuromuscular Research Institute

    RECRUITING

    Austin, Texas, 78756, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Profound Research LLC - Carlsbad

    RECRUITING

    Carlsbad, California, 92011, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UZ Leuven - PPDS

    RECRUITING

    Leuven, 3000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Visionary Investigators Network

    RECRUITING

    Miami, Florida, 33176, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.