New hope for GVHD patients after multiple failed treatments
NCT ID NCT03604692
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 28 times
Summary
This study tested a drug called axatilimab in 41 people with chronic graft-versus-host disease (cGVHD), a complication after a stem cell transplant where donor cells attack the body. Participants had already tried at least 2 other treatments. The goal was to find a safe dose and see if the drug could improve symptoms. Results showed some patients had partial or complete improvement.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope
Duarte, California, 91010, United States
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Fred Hutchinson Cancer Research Center
Seattle, Washington, 98109, United States
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Indiana University Health Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, 46202, United States
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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University of Miami Miller School of Medicine
Miami, Florida, 33136, United States
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University of Minnesota Medical Center
Minneapolis, Minnesota, 55455, United States
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University of Utah Health Huntsman Cancer Institute
Salt Lake City, Utah, 84112, United States
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Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37212-3505, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.