Promising new combo aims to shrink tumors and cut radiation in kids with hodgkin lymphoma

NCT ID NCT01920932

First seen Jan 04, 2026 · Last updated Jun 15, 2026 · Updated 24 times

Summary

This study tests a new treatment for children and teens with high-risk Hodgkin lymphoma. It combines the targeted drug Adcetris with standard chemotherapy and, if needed, radiation. The goal is to see if this approach can shrink tumors faster and reduce the need for radiation therapy. About 77 participants with stage IIB, IIIB, or IV disease are being enrolled.

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Contacts and locations

Locations

  • Dana-Farber Harvard Cancer Center

    Boston, Massachusetts, 02115, United States

  • Lucile Packard Children's Hospital Stanford University

    Palo Alto, California, 94304, United States

  • Maine Children's Cancer Program (MCCP)

    Scarborough, Maine, 04704, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • St. Jude Midwest Affiliate

    Peoria, Illinois, 61637, United States

Conditions

Explore the condition pages connected to this study.