Study links structural racism to teen brain changes and substance use risk

NCT ID NCT06221839

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study looks at how structural racism—like unequal access to resources—might affect brain structure and decision-making in Puerto Rican teens aged 11 to 14. Researchers will compare teens living in New York and Puerto Rico using interviews and brain scans. The goal is to understand if these social factors increase the risk of substance use, which could guide future prevention efforts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could reveal how societal factors like structural racism influence teen brain development and substance use risk, pointing toward better prevention strategies.
What could go wrong
This is an early observational study with only 72 participants, so findings may not apply to all groups. It measures associations, not cause and effect, and may not lead to direct interventions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Adolescent Behavior Systemic Racism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

  • University of Puerto Rico, Medical Sciences Campus

    RECRUITING

    San Juan, 00921, Puerto Rico