Brain stimulation may boost swallowing recovery after stroke

NCT ID NCT07793799

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial tests whether adding brain stimulation techniques to standard swallowing therapy helps people who have trouble swallowing after a stroke. Researchers will compare neuromuscular electrical stimulation (NMES) alone with NMES combined with either transcranial direct current stimulation (tDCS) or transcranial magnetic stimulation (TMS). Forty adults with post-stroke dysphagia will receive 10 treatment sessions, and their swallowing function will be measured before and after using X-ray and clinical assessments. The goal is to see if the combined approaches improve swallowing safety and reduce the severity of the swallowing disorder.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Neuromuscular electrical stimulation (NMES) alone or combined with transcranial direct current stimulation (tDCS) or transcranial magnetic stimulation (TMS)
What this could lead to
If combining brain stimulation with standard therapy improves swallowing, it could point to a more effective rehabilitation approach for people recovering from stroke.
What could go wrong
This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. The added brain stimulation might not provide extra benefit over standard therapy, and there are risks like discomfort or rare side effects from the devices.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2024

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 years or older * Diagnosis of ischemic or hemorrhagic stroke * Diagnosis of hemispheric stroke * Presence of swallowing difficulty or symptoms of dysphagia * Ability to cooperate and follow instructions * Absence of skin problems or abnormal tissue growth that would interfere with electrode placement Exclusion Criteria: * Presence of typical neurological findings suggestive of brainstem stroke * Inadequate sitting balance or inability to maintain the head in an upright position, with or without support * Presence of a neoplastic disease in the head and neck region or a history of radiotherapy to this region * Presence of an additional musculoskeletal disorder that may cause swallowing impairment * Presence of a neurological disorder other than stroke that may cause swallowing impairment, including traumatic brain injury, Parkinson's disease, dementia, amyotrophic lateral sclerosis, or multiple sclerosis * Presence of a cardiac pacemaker, deep brain stimulator, or ear tube * History of epileptic seizures * Presence of a metallic implant in the body or skull

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Conditions

The condition(s) this trial relates to.

Deglutition Disorders stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • Istinye Bahçeşehir Liv Hospital

    Istanbul, Turkey (Türkiye)

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