Brain stimulation may boost swallowing recovery after stroke
NCT ID NCT07793799
First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time
Summary
This trial tests whether adding brain stimulation techniques to standard swallowing therapy helps people who have trouble swallowing after a stroke. Researchers will compare neuromuscular electrical stimulation (NMES) alone with NMES combined with either transcranial direct current stimulation (tDCS) or transcranial magnetic stimulation (TMS). Forty adults with post-stroke dysphagia will receive 10 treatment sessions, and their swallowing function will be measured before and after using X-ray and clinical assessments. The goal is to see if the combined approaches improve swallowing safety and reduce the severity of the swallowing disorder.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Neuromuscular electrical stimulation (NMES) alone or combined with transcranial direct current stimulation (tDCS) or transcranial magnetic stimulation (TMS)
- What this could lead to
- If combining brain stimulation with standard therapy improves swallowing, it could point to a more effective rehabilitation approach for people recovering from stroke.
- What could go wrong
- This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. The added brain stimulation might not provide extra benefit over standard therapy, and there are risks like discomfort or rare side effects from the devices.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2024
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18 years or older * Diagnosis of ischemic or hemorrhagic stroke * Diagnosis of hemispheric stroke * Presence of swallowing difficulty or symptoms of dysphagia * Ability to cooperate and follow instructions * Absence of skin problems or abnormal tissue growth that would interfere with electrode placement Exclusion Criteria: * Presence of typical neurological findings suggestive of brainstem stroke * Inadequate sitting balance or inability to maintain the head in an upright position, with or without support * Presence of a neoplastic disease in the head and neck region or a history of radiotherapy to this region * Presence of an additional musculoskeletal disorder that may cause swallowing impairment * Presence of a neurological disorder other than stroke that may cause swallowing impairment, including traumatic brain injury, Parkinson's disease, dementia, amyotrophic lateral sclerosis, or multiple sclerosis * Presence of a cardiac pacemaker, deep brain stimulator, or ear tube * History of epileptic seizures * Presence of a metallic implant in the body or skull
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Istinye Bahçeşehir Liv Hospital
Istanbul, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Effects of transcranial direct current stimulation and pelvic proprioceptive neuromuscular facilitation on trunk control, balance and functional mobility in stroke patients
- Correlation of visual and motor deficits in stroke patients
- Pilot study on the effects induced by an electromyographic-controlled functional electrical stimulator (FitFES) for upper limb rehabilitation in post-stroke patients
- Brazilian version of a behavior change intervention to support healthy lifestyle adoption after stroke - iVIDAVC: protocol for a pilot randomized study
- Determination of efficacy of sustained motor contraction generated using StimWave peripheral nerve stimulator
- Can a PET tracer reveal hidden brain inflammation?