Could a steroid shot after stroke clot removal save more brain?
NCT ID NCT07141303
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study tests whether giving the steroid methylprednisolone right after a stroke clot removal helps patients recover better. About 1060 adults who had a major stroke will receive either the drug or a placebo. The goal is to see if it reduces disability, bleeding, and death.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Tangdu Hospital
RECRUITINGXi'an, Shaanxi, 710038, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
methylprednisolone sodium succinate (a steroid anti-inflammatory drug)
What this could lead to
If it works, this could become a standard add-on treatment to improve recovery and reduce brain swelling after stroke clot removal.
What could go wrong
This is a large Phase 3 trial, but steroids can increase infection risk and may not improve outcomes. The benefit over placebo is unproven.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.