New combo therapy shows promise for deadly lung disease Flare-Ups

NCT ID NCT03286556

First seen Feb 28, 2026 · Last updated May 23, 2026 · Updated 10 times

Summary

This study tested a treatment for people with idiopathic pulmonary fibrosis (IPF) who experience sudden, severe worsening of their condition. The treatment combined plasma exchange, rituximab, and intravenous immunoglobulin to target harmful antibodies. The goal was to improve survival during these dangerous episodes. The study included 82 adults aged 40-85 with confirmed IPF and recent worsening symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor University Medical Center

    Houston, Texas, 77030, United States

  • Dan Dilling

    Chicago, Illinois, 60611, United States

  • Temple University Hospital

    Philadelphia, Pennsylvania, 19140, United States

  • Thomas Jefferson University Medical Center

    Philadelphia, Pennsylvania, 19107, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Utah Medical Center

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.