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Stress hormone may cloud gut instincts, study suggests

NCT ID NCT07702747

Knowledge-focused Sponsor: Marie-France Marin Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study investigates whether acute psychosocial stress and the stress hormone cortisol alter the gut feelings that guide decision-making. Healthy young adults are randomly assigned to a stressful or control condition, then play a gambling task that measures risky versus safe choices. Saliva samples and skin sensors track stress responses and emotional signals. The goal is to understand how stress might cloud intuition and lead to riskier decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
psychosocial stress induction via the Trier Social Stress Test
What this could lead to
If it works, this could reveal how stress hormones like cortisol influence gut feelings and decision-making, potentially informing strategies to improve judgment under pressure.
What could go wrong
This is a small, early-stage study in healthy volunteers, so findings may not apply to real-world high-stakes decisions or people with stress-related disorders.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

116 people

The number who actually took part.

Started

Sep 2021

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult aged 18-35 years old. Exclusion Criteria: * Current or past psychiatric/neurodevelopmental disorders * Physical illness * Medication use (except hormonal contraception) * Alcohol consumption exceeding Health Canada guidelines (\>10 drinks/week for women, \>15 for men) * Smoking more than 7 cigarettes/day.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy young adults

Contacts and locations

Locations

  • Centre de recherche de l'Institut universitaire en santé mentale de Montréal

    Montreal, Quebec, H1N3M5, Canada

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