Leukemia drug holiday: study finds many can stop imatinib without relapse
NCT ID NCT01343173
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 1 time
Summary
This study looked at 220 adults with chronic myeloid leukemia who had been in deep remission for at least two years while taking imatinib. Researchers wanted to see if stopping the drug would cause the cancer to come back. They found that many patients stayed in remission after stopping, and they identified factors that help predict who can safely stop treatment without relapse.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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C.H.U. Brabois
Vandœuvre-lès-Nancy, 54500, France
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CH Annecy
Annecy, France
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CH Bretagne Atlantique
Vannes, France
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CH Régional de l'ILE DE LA REUNION/ Groupe Hospitalier Sud
Saint-Pierre, France
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CH Sud Francilien
Corbeil-Essonnes, France
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CH Valence
Valence, France
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CH Yves Le Foll
Saint-Brieuc, France
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CHR La Réunion
Saint-Denis, 97405, France
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CHU Bensançon
Besançon, France
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CHU Caen
Caen, France
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CHU Dupuytren
Limoges, France
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CHU Grenoble
Grenoble, 38043, France
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CHU Hôtel-Dieu
Nantes, 44035, France
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CHU de Nice - Hôpital Archet 1
Nice, 06202, France
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Centre Henri Becquerel
Rouen, France
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Centre Hospitalier - La Roche sur Yon
La Roche-sur-Yon, 85025, France
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Centre Hospitalier de Nevers
Nevers, 58033, France
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Centre Hospitalier de Versailles - Hôpital André Mignot
Versailles, 78157, France
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Hôpital Edouard Herriot
Lyon, 69374, France
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Hôpital Henri-Mondor
Créteil, 94000, France
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Hôpital Morvan
Brest, 29285, France
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Hôpital Necker-Enfants Malades
Paris, 75743, France
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Hôpital Pontchaillou
Rennes, 35033, France
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Hôpital Purpan
Toulouse, 31059, France
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Hôpital Saint Louis
Paris, 75475, France
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Hôpitaux civils de Colmar
Colmar, 68000, France
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Institut Bergonié
Bordeaux, 33076, France
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Institut Paoli Calmette
Marseille, 13273, France
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Lille University hospital - Hôpital Claude Huriez
Lille, 59037, France
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University Hospital Angers
Angers, 49033, France
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University Hospital Bordeaux, Hôpital du Haut Lévêque
Pessac, 33604, France
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University Hospital Poitiers - Hôpital Jean Bernard
Poitiers, 86021, France