Heart hole closure may cut stroke risk in seniors – landmark trial underway

NCT ID NCT05907694

Recruiting now Prevention Sponsor: Josep Rodes-Cabau Source: ClinicalTrials.gov ↗

First seen Apr 01, 2026 · Last updated May 16, 2026 · Updated 10 times

Summary

This study tests whether closing a common heart defect called PFO (a small hole between the heart's upper chambers) can prevent repeat strokes in people over 60 who have already had a stroke of unknown cause. About 714 older adults will receive either medication alone or medication plus a minimally invasive procedure to close the hole. The goal is to see if the closure reduces the chance of having another stroke.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

IUCPQ
RECRUITING

Québec, Quebec, G2E4G9, Canada

Contact Phone: •••-•••-•••• Email: •••••@•••••
IUCPQ-UL
ACTIVE_NOT_RECRUITING

Québec, Quebec, G1V 4G5, Canada

Conditions

Explore the condition pages connected to this study.

CRYPTOGENIC STROKE MEDICAL TREATMENT MEDICAL TREATMENT OLDER PATIENTS PATENT FORAMEN OVALE RECURRENT STROKE