New drug combo aims to tame rare inflammatory disease

NCT ID NCT07625384

Not yet recruiting Disease control Sponsor: R-Pharm International, LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two experimental drugs, goflikicept and olokizumab, in 52 adults with Still's disease, a rare inflammatory condition. The goal is to see if these drugs can quickly bring the disease under control and keep it from flaring up. Participants will receive either the study drugs or a placebo, and researchers will monitor symptoms like fever, rash, and joint pain for 24 weeks.

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Conditions

The condition(s) this trial relates to.

adult-onset Still disease juvenile idiopathic arthritis systemic-onset juvenile idiopathic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STILL DISEASE

Contacts and locations

Locations

"Vashe Zdorovie" Research Medical Complex, LLC

Kazan', 420097, Russia
"Zdorovaya Semya" Medical Center

Novosibirsk, 630099, Russia
Budgetary Healthcare Institution of the Omsk Region "Regional Clinical Hospital"

Omsk, 644111, Russia
Family Clinic No. 4, LLC

Korolyov, 141060, Russia
Federal Research Center "Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences"

Novosibirsk, 630117, Russia
I.M. Sechenov First Moscow State Medical University, University Clinical Hospital No. 3, E.M. Tareev Clinic of Rheumatology, Nephrology and Occupational Pathology

Moscow, 119435, Russia
Interleukin LLC

Saint Petersburg, 194214, Russia
Limited Liability Company "Firm ORIS"

Moscow, 117321, Russia
Limited Liability Company "Medical Technologies"

Saint Petersburg, 191025, Russia
Limited Liability Company "Medical-Sanitary Unit No. 157" (MSU No. 157)

Saint Petersburg, 196066, Russia
Limited Liability Company "OLLA-MED"

Moscow, 105554, Russia
Republic Clinical and Diagnostic Center of the Ministry of Health of the Udmurt Republic

Izhevsk, 426009, Russia
Russian Gerontology Clinical Research Center (RGNC) of Pirogov Russian National Research Medical University

Moscow, 129226, Russia
Siberian State Medical University (Federal State Budgetary Educational Institution of Higher Education of the Ministry of Health of the Russian Federation)

Tomsk, 634050, Russia
Smolensk Regional Rheumatology Center at the "RZD-Medicine" Clinical Hospital (Private Healthcare Institution)

Smolensk, 214025, Russia
State Budgetary Healthcare Institution "A.S. Loginov Moscow Clinical Scientific Center of the Moscow Department of Healthcare"

Moscow, 111123, Russia
State Budgetary Healthcare Institution "G.G. Kuvatov Republican Clinical Hospital"

Ufa, 450005, Russia
State Budgetary Healthcare Institution "Leningrad Regional Clinical Hospital"

Saint Petersburg, 194291, Russia
State Budgetary Healthcare Institution "Orenburg Regional Clinical Hospital named after V.I. Voynov"

Orenburg, 460018, Russia
State Budgetary Healthcare Institution "V.A. Baranov Republican Hospital"

Petrozavodsk, 185000, Russia
State Budgetary Healthcare Institution of the City of Moscow "N.I. Pirogov City Clinical Hospital No. 1 of the Moscow Department of Healthcare"

Moscow, 119049, Russia
State Healthcare Institution "City Clinical Emergency Hospital No. 25"

Volgograd, 400117, Russia
State Healthcare Institution "Regional Clinical Hospital" of Saratov

Saratov, 410053, Russia
V.A. Nasonova Research Institute of Rheumatology (Federal State Budgetary Scientific Institution)

Moscow, 115522, Russia
Yaroslavl State Medical University (Federal State Budgetary Educational Institution of Higher Education of the Ministry of Health of the Russian Federation)

Yaroslavl, 150047, Russia

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