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Can a steroid shot stop nerve pain after back pain treatment?

NCT ID NCT07839195

Prevention Sponsor: Siriraj Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 24, 2026 · Last updated Sep 25, 2026 · Updated 1 time

Summary

Radiofrequency neurotomy uses heat to quiet nerves that carry pain from facet joints and the sacroiliac joint. Some patients develop a new burning or tingling pain afterward, called post-neurotomy neuritis. This trial randomly assigns adults having the procedure to receive either a local injection of dexamethasone with bupivacaine or bupivacaine alone at the treated sites. Researchers compare how often post-neurotomy neuritis occurs and track pain scores, function, and side effects over four weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone, a corticosteroid, mixed with bupivacaine, a local anesthetic
What this could lead to
If it works, this could give doctors a simple way to reduce nerve pain after radiofrequency neurotomy for chronic spine and sacroiliac joint pain.
What could go wrong
This is a Phase 2 trial with 126 people, so it may not show a clear benefit. Steroid injections carry small risks of infection, bleeding, or temporary pain at the injection site.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 126 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patient who aged equal and over 18 years old 2. Patient who scheduled for cervical, thoracic, and lumbar medial branch RFN and sacral lateral branch RFN 3. Patient who communicated effectively, demonstrated good understanding of questions and provided appropriate responses Exclusion Criteria: 1. Contraindications to corticosteroids: Patients with a known allergy or hypersensitivity to dexamethasone or other glucocorticoids 2. Contraindications to local anesthetics: Patients with a history of severe allergic reactions to amide-type local anesthetics (e.g., bupivacaine) 3. Active Infection: Presence of localized infection at the planned injection site or systemic infection (sepsis) that may contraindicate the procedure 4. Coagulopathy: Patients with uncorrected bleeding disorders or those unable to safely discontinue anticoagulant/antiplatelet medications according to standard procedural guidelines 5. Pregnancy or Lactation: Pregnant or breastfeeding women, due to potential risks associated with radiation (fluoroscopy) and medication exposure 6. Recent Corticosteroid Exposure: Patients who have received systemic or local corticosteroid injections at the target site within the past 3 months, which may interfere with the study outcomes 7. Unstable Neurological Conditions: Patients with progressive neurological deficits or acute radiculopathy that requires urgent surgical intervention

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Conditions

The condition(s) this trial relates to.

arthropathy Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arthropathy Chronic pain Facet joint pain Post-neurotomy neuritis Sacroiliac joint dysfunction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Siriraj pain clinic, Department of Anesthesiology, Faculty of Medicine Siriraj hospital

    Bangkok, 10700, Thailand

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