Radical stem cell 'Reset' tested as last hope for tough MS cases

NCT ID NCT04047628

Summary

This study is testing whether a stem cell transplant can better control multiple sclerosis (MS) than the best available drugs in people whose MS stays active despite treatment. It will involve 156 adults whose MS has flared up despite taking strong medications. Participants will be randomly assigned to receive either the stem cell transplant procedure or continue with the most effective drug therapy, and researchers will follow them for six years to see which approach works better.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinical Research Division, Fred Hutchinson Cancer Research Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Corinne Goldsmith Dickinson Center for Multiple Sclerosis at Mount Siinai

    RECRUITING

    New York, New York, 10029, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Medical Center

    ACTIVE_NOT_RECRUITING

    Durham, North Carolina, 27710, United States

  • John L. Trotter Multiple Sclerosis Center, Washington University School of Medicine in St. Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maxine Mesigner Multiple Sclerosis Comprehensive Care Center, Baylor College of Medicine Medical Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Multiple Sclerosis Center at Northwest Hospital

    RECRUITING

    Seattle, Washington, 98133, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Multiple Sclerosis Center, Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Multiple Sclerosis Center, Swedish Neuroscience Institute

    RECRUITING

    Seattle, Washington, 98122, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Northwestern University

    RECRUITING

    Evanston, Illinois, 60208, United States

    Contact

    Contact

    Contact Email: •••••@•••••

  • Penn Comprehensive MS Center, Hospital of the University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rochester Multiple Sclerosis Center, University of Rochester

    NOT_YET_RECRUITING

    Rochester, New York, 14620, United States

    Contact

  • Rocky Mountain Multiple Sclerosis Center, University of Colorado School of Medicine

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford Multiple Sclerosis Center

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Cincinnati (UC) Waddell Center for Multiple Sclerosis

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Massachusetts Memorial Medical Center

    RECRUITING

    Worcester, Massachusetts, 01655, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Minnesota Multiple Sclerosis Center

    ACTIVE_NOT_RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • University of Texas Southwestern Medical Center: Division of Multiple Sclerosis and Neuroimmunology

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Virginia Commonwealth University Multiple Sclerosis Treatment and Research Center

    RECRUITING

    Richmond, Virginia, 23219, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.