New hope for older AML patients: gentler transplant approach aims to boost survival with less toxicity
NCT ID NCT07598110
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a reduced-intensity chemotherapy combination (fludarabine and treosulfan) before a half-matched stem cell transplant in 77 older or frail adults with AML. The goal is to see if this gentler regimen can control the leukemia long-term while being safe enough for patients who cannot tolerate standard high-dose chemo. Participants will receive the transplant and then be followed for relapse and side effects.
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Conditions
The condition(s) this trial relates to.
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