New hope for older AML patients: gentler chemo before transplant may boost survival

NCT ID NCT07598110

First seen May 23, 2026 · Last updated May 23, 2026

Summary

This study tests a milder chemotherapy combination (fludarabine and treosulfan) given before a stem cell transplant from a half-matched donor for older or frail adults with acute myeloid leukemia (AML). The goal is to see if this approach can help control the cancer longer while being easier on the body. About 77 participants aged 60-75 (or younger if too frail for standard chemo) will be enrolled. After the transplant, patients receive standard follow-up care and extra questionnaires.

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Contacts and locations

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