New hope for older blood cancer patients: smarter transplants on the horizon

NCT ID NCT04217278

First seen May 18, 2026 · Last updated May 24, 2026 · Updated 2 times

Summary

This study looks at ways to improve stem cell transplants for older adults with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). It compares different pre-transplant and conditioning therapies to reduce relapse and improve survival. About 333 participants are being followed for at least 2 years after transplant.

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Contacts and locations

Locations

  • Addenbrooke's Hospital

    Cambridge, United Kingdom

  • Churchill Hospital

    Oxford, United Kingdom

  • Derriford Hospital

    Plymouth, United Kingdom

  • Freeman Hospital

    Newcastle, United Kingdom

  • Hammersmith Hospital

    London, United Kingdom

  • King's College Hospital

    London, United Kingdom

  • Leicester Royal Infirmary

    Leicester, United Kingdom

  • Manchester Royal Infirmary

    Manchester, United Kingdom

  • Nottingham City Hospital

    Nottingham, United Kingdom

  • Queen Elizabeth Hospital

    Birmingham, United Kingdom

  • Queen Elizabeth Hospital Glasgow

    Glasgow, United Kingdom

  • St James' University Hospital

    Leeds, United Kingdom

  • University Hospital of Wales

    Cardiff, United Kingdom

  • University Hospitals Bristol

    Bristol, United Kingdom

Conditions

Explore the condition pages connected to this study.