New hope for blood cancer patients: trial tests better protection after transplants

NCT ID NCT06859424

Summary

This study aims to find the best drug combination to prevent graft-versus-host disease (GVHD), a serious complication where donor immune cells attack the patient's body after a stem cell transplant. Researchers are comparing two new drug combinations against the current standard treatment in 358 patients with blood cancers who receive stem cells from partially matched, unrelated donors. The goal is to improve survival without GVHD or cancer returning while monitoring safety.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02446, United States

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

  • Karmanos Cancer Institute

    RECRUITING

    Detroit, Michigan, 48201, United States

  • MD Anderson

    RECRUITING

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering

    RECRUITING

    New York, New York, 10065, United States

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Stanford

    RECRUITING

    Palo Alto, California, 94304, United States

  • University of Alabama Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

  • University of Kansas Medical Center

    RECRUITING

    Westwood, Kansas, 66205, United States

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

  • University of North Carolina

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22903, United States

Conditions

Explore the condition pages connected to this study.