New transplant approach offers hope for rare immune and bone marrow diseases

NCT ID NCT04232085

First seen Jan 04, 2026 · Last updated Apr 23, 2026 · Updated 16 times

Summary

This study tests a stem cell transplant using milder chemotherapy and a drug called cyclophosphamide after transplant to help the body accept donor cells. It is for people with primary immune deficiencies, immune dysregulation, or inherited bone marrow failure. The goal is to see if donor stem cells can successfully take over and restore healthy blood and immune function.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.