New combo therapy aims to tame tough Crohn's cases
NCT ID NCT03219359
First seen Nov 05, 2025 · Last updated May 20, 2026 · Updated 30 times
Summary
This study tests whether a stem cell transplant followed by the drug vedolizumab can help people with severe Crohn's disease that hasn't responded to other treatments. About 50 adults with active Crohn's will receive high-dose chemotherapy, a stem cell transplant, and then vedolizumab for several months. The goal is to see if this approach can put the disease into remission and keep it under control for at least a year.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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