Scientists test 'Goldilocks' drug dose to make transplants safer

NCT ID NCT05166967

Summary

This study tested whether a personalized dose of a drug called ATG works better than a standard fixed dose for patients receiving a stem cell transplant from a half-matched donor. The goal was to find the dose that best prevents a dangerous complication where the donor cells attack the patient's body (graft-versus-host disease), while also keeping the risk of serious viral infections low. Researchers compared the two dosing approaches in 204 patients to see which led to better overall outcomes.

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Contacts and locations

Locations

  • Chinese PLA General Hospital

    Beijing, Beijing Municipality, 100853, China

Conditions

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