Stem cells tested to keep Crohn's disease under control

NCT ID NCT00543374

Completed Disease control Sponsor: Mesoblast, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested whether an infusion of donor stem cells could help people with moderate-to-severe Crohn's disease who don't respond to standard treatments. It focused on patients who had already shown some improvement from the cells in a previous trial, checking how long that benefit lasted and if a second dose could restart improvement. The goal was to see if this therapy could provide lasting control of the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Advanced Clinical Research Institute

Anaheim, California, 92801, United States
Allegheney Center for Digestive Health

Pittsburgh, Pennsylvania, 15212, United States
Atlanta Gastroenterology Associates

Atlanta, Georgia, 30342, United States
Baylor University Medical Center

Dallas, Texas, 75246, United States
Borland-Groover Clinic

Jacksonville, Florida, 32256, United States
Brigham and Womens Hospital

Boston, Massachusetts, 02115, United States
Carle Clinic Association

Urbana, Illinois, 61801, United States
Center for Clinical Studies

Dearborn, Michigan, 48124, United States
Center for Digestive Health

Troy, Michigan, 48098, United States
Charlotte Gastroenterology and Hepatology

Charlotte, North Carolina, 28207, United States
Clinical Pharmacology Study Group

Worcester, Massachusetts, 01610, United States
Clinical Research of West Florida

Clearwater, Florida, 33765, United States
Cotton-O'Neil Clinical Research Center

Topeka, Kansas, 66606, United States
Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States
Dayton Science Institute

Dayton, Ohio, 45415, United States
Digestive and Liver Disease Specialists

Norfolk, Virginia, 23502, United States
Gastroenterology Center of Connecticut

Hamden, Connecticut, 06518, United States
Gastroenterology Center of the Midsouth

Germantown, Tennessee, 37138, United States
Gastroenterology Research Associates

Cedar Knolls, New Jersey, 07927, United States
Gastroenterology United of Tulsa

Tulsa, Oklahoma, 74135, United States
Gulf Coast Research

Baton Rouge, Louisiana, 70808, United States
Health Sciences Centre

Winnipeg, Manitoba, R3A 1R9, Canada
Holy Name Hospital

Teaneck, New Jersey, 07666, United States
Indiana University Medical Center

Indianapolis, Indiana, 46202, United States
London Health Sciences Centre

London, Ontario, N6A 5A5, Canada
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
McGuire Research Institute

Richmond, Virginia, 23249, United States
Memorial Hermann Hospital

Houston, Texas, 77030, United States
Metropolitan Gastroenterology Group

Chevy Chase, Maryland, 20815, United States
Mount Sinai Hospital

Toronto, Ontario, M5G 1X5, Canada
Mount Sinai School of Medicine

New York, New York, 10029, United States
Nashville GI Specialists

Nashville, Tennessee, 37205, United States
National Institutes of Health

Bethesda, Maryland, 20892, United States
Options Health Research

Tulsa, Oklahoma, 74137, United States
Pinehurst Medical Clinic

Pinehurst, North Carolina, 28734, United States
Rochester General Hospital

Rochester, New York, 14621, United States
Rochester Institute for Digestive Diseases

Rochester, New York, 14607, United States
Seattle Gastroenterology Associates

Seattle, Washington, 98133, United States
Shafran Gastroenterology Center

Winter Park, Florida, 32789, United States
St Louis Center for Clinical Studies

St Louis, Missouri, 63128, United States
University Hospital and Medical Center

Stony Brook, New York, 11794, United States
University of Alberta Hospital

Edmonton, Alberta, T6G 2X8, Canada
University of Calgary

Calgary, Alberta, T2N 4N1, Canada
University of California, San Francisco

San Francisco, California, 94115, United States
University of Chicago Medical Center

Chicago, Illinois, 60637, United States
University of Kentucky Hospital

Lexington, Kentucky, 40536, United States
University of Louisville Hospital

Louisville, Kentucky, 40202, United States
University of Minnesota Hospital

Minneapolis, Minnesota, 55455, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States
University of Southern California University Hospital

Los Angeles, California, 90033, United States
University of Texas Medical Branch

Galveston, Texas, 77555, United States
University of Vermont

Burlington, Vermont, 05401, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Venture Research Institute

Miami, Florida, 33162, United States
Veteran's Administration Medical Center (does not require vet status)

Long Beach, California, 90822, United States
Wake Forest University

Winston-Salem, North Carolina, 27157, United States
Weill Cornell Medical College

New York, New York, 10028, United States
Western States Clinical Research

Wheat Ridge, Colorado, 80033, United States

Conditions

Explore the condition pages connected to this study.

CROHN'S DISEASE