Higher stem cell dose may boost immune recovery after lymphoma treatment
NCT ID NCT02570542
Summary
This study investigates whether giving a higher dose of a patient's own stem cells during transplant leads to better immune system recovery and outcomes for people with aggressive lymphoma that has returned or resisted treatment. Participants with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) were randomly assigned to receive either a standard or a higher dose of their collected stem cells. The main goal is to see if the higher dose improves progression-free survival by helping the immune system recover faster after the intensive transplant procedure.
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Contacts and locations
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Locations
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Columbia University
New York, New York, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Memorial Sloan Kettering Basking Ridge (Consent and Follow-Up Only)
Basking Ridge, New Jersey, United States
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Memorial Sloan Kettering Bergen (Consent and Follow Up Only)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack (Consent and Follow-up Only)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (Consent and Follow up Only)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (Consent and Follow up Only)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester
Harrison, New York, 10604, United States
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Northwell Health (Data collection only)
Manhasset, New York, 11030, United States
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Tennessee Oncology
Nashville, Tennessee, 37203, United States
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Texas Transplant Institute
San Antonio, Texas, 78229, United States
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University of Nebraska Medical Center
Omaha, Nebraska, 68198-7680, United States
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University of Rochester Medical Center
Rochester, New York, 14642, United States
Conditions
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