Could a simple vitamin boost plaque stability and cut stroke risk?
NCT ID NCT07680595
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study investigates whether adding folic acid to standard statin therapy can make carotid artery plaques more stable, potentially reducing stroke risk. Researchers will enroll 180 adults aged 18 to 75 with carotid plaque buildup, giving half of them atorvastatin alone and the other half atorvastatin plus folic acid for six months. The main goal is to see if the combination reduces plaque thickness more than statins alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
atorvastatin and folic acid
What this could lead to
If adding folic acid to statins improves plaque stability, it could lead to a simple, low-cost way to lower stroke risk in people with carotid artery disease.
What could go wrong
This is an early exploratory study with only 180 participants, so results may not apply broadly. The 6-month treatment period is short, and the benefits of folic acid on plaque stability are not yet proven.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shanghai Jiao Tong University Medical School Affiliated Ruijing Hospital
RECRUITINGShanghai, Shanghai Municipality, 200433, China
Contact Phone: •••-•••-•••• Email: •••••@•••••