Cholesterol drug may unleash immune system against prostate cancer

NCT ID NCT05586360

First seen Mar 14, 2026 · Last updated May 12, 2026 · Updated 9 times

Summary

This study tests whether simvastatin, a common cholesterol medication, can help the immune system better attack prostate cancer. Men with localized prostate cancer who are planning to have surgery will be randomly assigned to take simvastatin for 8 weeks before their operation or to receive standard care. Researchers will then compare immune activity in the removed prostate tissue to see if the statin made a difference.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Emory University

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • Hollings Cancer Center at Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

    Contact

Conditions

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