New drug combo aims to shrink brain tumors in advanced cancer
NCT ID NCT05700721
First seen Nov 19, 2025 · Last updated May 10, 2026 · Updated 18 times
Summary
This study tests whether two drugs, niraparib and dostarlimab, can control advanced cancers that have spread to the brain. About 120 adults with certain cancer types (like BRCA-mutated cancers, lung cancer, or triple-negative breast cancer) and growing brain tumors will receive the combination. The goal is to see if the treatment can stop or slow the brain metastases, but it is not expected to be a cure.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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