New gene therapy injection aims to halt vision loss in stargardt disease
NCT ID NCT07161544
First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 28 times
Summary
This study tests a one-time gene therapy injection (AAVB-039) into the eye for people with Stargardt disease, a genetic condition that causes progressive vision loss. The trial involves 75 participants and will first check safety, then measure if the treatment can slow damage to the retina. It is for people with confirmed ABCA4 gene mutations who are healthy enough for eye surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Moorfields Eye Hospital NHS Foundation Trust
RECRUITINGLondon, England, EC1V 2PD, United Kingdom
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Retina Consultants of Texas
RECRUITINGBellaire, Texas, 77401, United States
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Retina Foundation of the Southwest
RECRUITINGDallas, Texas, 75231, United States
Contact Email: •••••@•••••
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Retina Vitreous Associates Medical Group
RECRUITINGLos Angeles, California, 90211, United States
Contact
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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The Retina Clinic
RECRUITINGLondon, England, W1G 9AX, United Kingdom
Conditions
Explore the condition pages connected to this study.