Tonsils shed light on staph Bacteria's secrets

NCT ID NCT06479837

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study aims to understand how Staphylococcus aureus bacteria interact with human cells to cause infections, especially in the spine. Researchers will use tonsil tissue discarded after routine tonsillectomies to create lab models. About 500 participants aged 2 and older who are scheduled for tonsil removal will provide a nasal swab and allow their tonsil tissue to be used for research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help researchers develop better treatments for serious Staph infections, including those in the spine.

What could go wrong

This is an early, observational study using donated tissue, not a treatment trial. It may not lead directly to new therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

staphylococcal infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institute of Allergy and Infectious Diseases (NIAID)

    RECRUITING

    Bethesda, Maryland, 20892, United States

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••