Radiation or surgery? new trial seeks best option for lung cancer patients

NCT ID NCT02468024

Recruiting now Disease control Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

First seen Nov 17, 2025 · Last updated Apr 28, 2026 · Updated 25 times

Summary

This study compares two treatments for early-stage non-small cell lung cancer in patients who are at high risk for surgery. One group will have a small part of the lung removed (sublobar resection), and the other will receive targeted radiation (stereotactic ablative radiotherapy). The goal is to see which treatment helps patients live longer with fewer side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Allegheny
RECRUITING

Pittsburgh, Pennsylvania, 15212, United States

Contact Email: •••••@•••••
Barwon Health - Uni Hospital Geelong
RECRUITING

Geelong, Victoria, 3220, Australia

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Beaumont
COMPLETED

Royal Oak, Michigan, 48073, United States
Boca Raton Regional Hospital
COMPLETED

Boca Raton, Florida, 33486, United States
Boston Medical Center
COMPLETED

Boston, Massachusetts, 02118, United States
CHUM
RECRUITING

Montreal, Quebec, 26214, Canada

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Cardiothoracic and Vascular Surgeons
COMPLETED

Austin, Texas, 78756, United States
Case Western (University Hospitals Case Medical Center)
COMPLETED

Cleveland, Ohio, 44106, United States
Clement Zablocki VA Medical Center
COMPLETED

Milwaukee, Wisconsin, 53295, United States
Cleveland Clinic
ACTIVE_NOT_RECRUITING

Cleveland, Ohio, 44195, United States
Curtis and Elizabeth Anderson Cancer
RECRUITING

Savannah, Georgia, 31404, United States

Contact Phone: •••-•••-••••
Henry Ford Health System
COMPLETED

Detroit, Michigan, 48202-2689, United States
Inova Fairfax Medical Campus
COMPLETED

Falls Church, Virginia, 22042, United States
Intermountain Medical Center
COMPLETED

Salt Lake City, Utah, 84107, United States
Lawson Health Science Center
RECRUITING

London, Ontario, Canada, N6C 2R5, Canada

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Lifespan Oncology Clinical Research
COMPLETED

Providence, Rhode Island, 02903, United States
Luminis Health Research Institute
ACTIVE_NOT_RECRUITING

Annapolis, Maryland, 21401, United States
Mayo Clinic Rochester
COMPLETED

Rochester, Minnesota, 55905, United States
Medical College of Wisconsin
COMPLETED

Milwaukee, Wisconsin, 53226, United States
Meridian Health System
RECRUITING

Neptune City, New Jersey, 07753, United States

Contact Email: •••••@•••••
Mount Nittany
COMPLETED

State College, Pennsylvania, 16803, United States
New York University Langone Medical Center
ACTIVE_NOT_RECRUITING

New York, New York, 10016, United States
Ochsner Medical Center
COMPLETED

New Orleans, Louisiana, 70121, United States
Ohio State University Wexner Medical Center
ACTIVE_NOT_RECRUITING

Columbus, Ohio, 43210, United States
Ottawa Hospital Cancer Center
RECRUITING

Ottawa, Ontario, KIH8L6, Canada

Contact Email: •••••@•••••

Contact Email: •••••@•••••
Penrose Cancer Center
COMPLETED

Colorado Springs, Colorado, 80907, United States
Providence Health & Services/Oregon Clinic
COMPLETED

Portland, Oregon, 97213, United States
SUNY - Upsate Medical Centre
RECRUITING

Syracuse, New York, 13210, United States

Contact Email: •••••@•••••

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St. Vincent's Hospital Melbourne
RECRUITING

Fitzroy, Melbourne, 3065, Australia

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact

Contact Email: •••••@•••••
St. Vincent's/Peter Mac
RECRUITING

Fitzroy, Victoria, 3065, Australia

Contact Email: •••••@•••••

Contact Email: •••••@•••••
Sunnybrook Health Sciences Centre
COMPLETED

Toronto, Canada, M4N 3M5, Canada
Swedish Cancer Institute
COMPLETED

Seattle, Washington, 98104, United States
The James Cook University Hospital
ACTIVE_NOT_RECRUITING

Middlesbrough, TS4 2BW, United Kingdom
Thomas Jefferson University
COMPLETED

Philadelphia, Pennsylvania, 19107, United States
Trillium Health Partners
COMPLETED

Mississauga, Canada, L5M 2N1, Canada
UCSD
COMPLETED

La Jolla, California, 92023, United States
UHN-Toronto
RECRUITING

Toronto, Ontario, M5G2C4, Canada

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UPMC Health System
COMPLETED

Pittsburgh, Pennsylvania, 15234, United States
University of Cincinnati
COMPLETED

Cincinnati, Ohio, 45267, United States
University of Colorado/Memorial
COMPLETED

Aurora, Colorado, 80045, United States
University of Iowa
TERMINATED

Iowa City, Iowa, 52242, United States
University of Kansas Medical Center
COMPLETED

Kansas City, Kansas, 66160, United States
University of Kentucky Health Care
COMPLETED

Lexington, Kentucky, 40536-0093, United States
University of Louisville Physicians
ACTIVE_NOT_RECRUITING

Louisville, Kentucky, 40202, United States
University of Maryland Medical Center
COMPLETED

Baltimore, Maryland, 21201, United States
University of North Carolina
COMPLETED

Chapel Hill, North Carolina, 27599, United States
University of Tennessee Health Science Center
COMPLETED

Memphis, Tennessee, 38163, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States

Contact Phone: •••-•••-••••

Contact
University of Virginia Health System
COMPLETED

Charlottesville, Virginia, 22901, United States
Wake Forest Baptist Health
COMPLETED

Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.

NON SMALL CELL LUNG CANCER NON-SMALL CELL LUNG CANCER