New shot aims to prevent clots without bleeding risk

NCT ID NCT07655427

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested a single injection of a new drug called SRSD107 in 48 healthy adults. The drug is designed to temporarily lower a clotting factor in the liver, potentially preventing dangerous blood clots with less bleeding risk than standard treatments. The main goal was to check safety and how the body processes the drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SRSD107 (a synthetic siRNA drug that targets a clotting factor to reduce blood clot risk)

What this could lead to

If successful, this could lead to a new injectable drug that lowers the risk of dangerous blood clots (like deep vein thrombosis or stroke) without increasing bleeding risk as much as current treatments.

What could go wrong

This is an early Phase 1 trial in only 48 healthy people, so safety and effectiveness are not yet proven. The drug may not work as expected or could cause unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Tiantan Hospital Affiliated to Capital Medical University

    Beijing, Beijing Municipality, China