Brain radiation plus drugs: a new hope for cancer patients?
NCT ID NCT05522660
First seen Oct 31, 2025 · Last updated Apr 29, 2026 · Updated 28 times
Summary
This study looks at whether adding a precise type of radiation (stereotactic radiosurgery) to standard drug treatments can better control brain metastases in people with melanoma or non-small cell lung cancer. About 180 participants with newly diagnosed, untreated brain metastases that cause few or no symptoms will be randomly assigned to receive either standard drugs alone or drugs plus radiation. The goal is to see which approach improves how long the brain cancer stays under control and overall quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azienda ospedaliero-universitaria Senese Siena
RECRUITINGSiena, Italy
Contact Email: •••••@•••••
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Christie NHS Manchester
RECRUITINGManchester, United Kingdom
Contact Email: •••••@•••••
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Hospital La Fe
RECRUITINGValencia, Spain
Contact Email: •••••@•••••
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Hospital Puerta de Hierro
RECRUITINGMajadahonda, Spain
Contact Email: •••••@•••••
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Inselspital
RECRUITINGBern, Switzerland
Contact Email: •••••@•••••
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Instituto Oncologico Veneto IRCCS
NOT_YET_RECRUITINGPadova, Italy
Contact Email: •••••@•••••
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Istituto Nazionale Tumori "Regina Elena"
RECRUITINGRoma, Italy
Contact Email: •••••@•••••
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Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
RECRUITINGNaples, Italy
Contact Email: •••••@•••••
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Kantonsspital Winterthur
RECRUITINGWinterthur, Switzerland
Contact Email: •••••@•••••
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NKI-AVL
RECRUITINGAmsterdam, Netherlands
Contact Email: •••••@•••••
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Policlinico Umberto 1
RECRUITINGRome, Italy
Contact Email: •••••@•••••
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Royal Marsden (Sutton)
RECRUITINGLondon, United Kingdom
Contact Email: •••••@•••••
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Santa Maria della Misericordia Hospital
RECRUITINGPerugia, Italy
Contact Email: •••••@•••••
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Universitätsspital Zürich
RECRUITINGZurich, Switzerland
Contact Email: •••••@•••••
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Vall Hebron Institute of Oncology (VHIO)
RECRUITINGBarcelona, Spain
Contact Email: •••••@•••••
Conditions
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