Zapping pain away: radiation therapy tested for chronic nerve pain

NCT ID NCT05985148

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tests whether a precise, one-time radiation treatment called stereotactic radiosurgery (SRS) can safely relieve chronic pain in the chest or abdominal wall. The pain must be linked to specific spinal nerves and not helped by standard pain medicines. Researchers will test three radiation doses in 18 people to find the safest and most effective dose.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
stereotactic radiosurgery (SRS)
What this could lead to
If successful, this could offer a non-invasive treatment option for people with chronic chest or abdominal wall pain that hasn't responded to standard therapies.
What could go wrong
This is a very early phase 1 trial with only 18 participants, so safety and effectiveness are not yet proven. There is a risk of nerve damage or other side effects from the radiation.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    RECRUITING

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States