New brain bleed treatment shows promise in major trial

NCT ID NCT04410146

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a procedure called middle meningeal artery embolization using a special gel (SQUID) to treat chronic subdural hematoma, a condition where blood collects between the brain and its outer covering. 319 adults with a large blood collection were randomly assigned to receive the procedure or standard care. The goal was to see if the procedure could reduce the need for repeat surgery and prevent complications like stroke or death within 180 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hematoma, Subdural, Chronic Hematoma, Subdural, Intracranial

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Locations

  • Baptist Health

    Jacksonville, Florida, 32207, United States

  • Baptist Memorial Hospital

    Memphis, Tennessee, 38120, United States

  • Barrow Neurological Institute

    Phoenix, Arizona, 85013, United States

  • CHU Hopital Bicetre

    Le Kremlin-Bicêtre, 94275, France

  • CHU Hopital Maison Blanche

    Reims, France

  • Carondolet St. Joseph's

    Tucson, Arizona, 85711, United States

  • Chu Cote de Nacre

    Caen, 14000, France

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Geisinger Medical Center

    Danville, Pennsylvania, 17822, United States

  • Gregorio Maranon Hospital

    Madrid, 28007, Spain

  • Hopital Pitie Salpetriere

    Paris, France

  • Johns Hopkins Medicine

    Baltimore, Maryland, 21287, United States

  • Klinikum Nurnberg Sud

    Nuremberg, Germany

  • Los Robles Hospital and Medical Center

    Thousand Oaks, California, 92360, United States

  • Methodist University Hospital

    Memphis, Tennessee, 38104, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Nebraska Health

    Omaha, Nebraska, 68106, United States

  • Overlook Medical Center

    Summit, New Jersey, 07901, United States

  • Penn State Health Hershey Medical Center

    Hershey, Pennsylvania, 17918, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Riverside Community Hospital

    Riverside, California, 92501, United States

  • Santa Barbara Cottage Hospital

    Santa Barbara, California, 93105, United States

  • Stony Brook University

    Stony Brook, New York, 11794, United States

  • Swedish Cherry Hill

    Seattle, Washington, 98122, United States

  • Swedish Medical Center

    Englewood, Colorado, 80113, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University of Kansas

    Kansas City, Kansas, 66160, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • Universitätsklinikum Heidelberg

    Heidelberg, Germany

  • Wellstar Kennestone Hospital

    Marietta, Georgia, 30060, United States

  • West Virginia University

    Morgantown, West Virginia, 26506, United States