New peptide cream promises better skin hydration – but is it hype?
NCT ID NCT07236736
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests a topical cream called SPM™ on 10 healthy adults to see if it improves skin hydration, appearance, and barrier function. Participants apply the cream twice daily for six weeks on one area, while an untreated area serves as a comparison. Skin hydration and small biopsies are taken before and after to look for changes in skin structure and moisture.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Super Protein Multifunction (SPM™) topical peptide-based formulation
- What this could lead to
- If it works, this could point toward a cosmetic product that improves skin hydration and barrier strength.
- What could go wrong
- This is a very small, early exploratory study with only 10 healthy adults. It is not designed to prove effectiveness, and results may not apply to people with skin conditions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Generally healthy with no systemic or active dermatologic diseases. 2. Willing and able to apply topical product daily for 6 weeks. 3. Able to provide written informed consent. 4. Willing to undergo skin biopsies and follow study procedures. Exclusion Criteria: 1. History of skin cancer or other malignancy within the past 10 years. 2. Active or chronic dermatologic conditions (e.g., eczema, psoriasis, acne, rosacea). 3. Known allergy or sensitivity to components of the investigational product. 4. Current use of systemic corticosteroids or immunosuppressants. 5. Pregnancy or breastfeeding. 6. Any condition that, in the investigator's opinion, would interfere with study participation or pose additional risk.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Project Quality of Life
West Hollywood, California, 90069, United States
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