New gel injection promises to quench thirsty skin
NCT ID NCT06821854
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study tested a gel called PN20 (Plinest) injected into the skin to improve hydration and elasticity. Twenty-five adults received up to three treatments on their face, neck, or décolleté. Researchers measured skin moisture, firmness, and appearance over six months to see if the gel works and is safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PN20 (Plinest) - a sterile gel containing polynucleotides injected into the skin
What this could lead to
If it works, this could offer a safe, non-surgical option to improve skin hydration and appearance for up to 4 months.
What could go wrong
This is a small, single-arm study with only 25 participants, so results may not apply to everyone. It is a cosmetic device, not a medical treatment for a disease.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinica di Chirurgia plastica e ricostruttiva/Ospedale Policlinico San Martino
Genova, Italy, 16132, Italy