Scientists probe Spleen's secrets to unlock blood disease mysteries

NCT ID NCT06418256

Recruiting now Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study aims to better understand how the spleen filters and responds to abnormal blood cells in various diseases. Researchers will collect spleen tissue and blood from 100 adults undergoing planned splenectomy. By perfusing the spleen in the lab, they hope to uncover its role in conditions like malaria and other blood disorders.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could clarify how the spleen contributes to diseases like malaria and blood disorders, potentially pointing toward new treatments.
What could go wrong: This is an observational, lab-based study, not a treatment trial. Findings may not directly translate to new therapies, and results are limited to the laboratory setting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hereditary spherocytosis malaria sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SPLENECTOMY

Contacts and locations

Locations

Hôpital Beaujon
RECRUITING

Clichy, 92110, France
Hôpital Necker-Enfants Malades
RECRUITING

Paris, 75015, France
Hôpital Pitié Salpêtrière
RECRUITING

Paris, 75013, France
Hôpital Saint Antoine
RECRUITING

Paris, 75012, France
Institut Pasteur
ACTIVE_NOT_RECRUITING

Paris, 75015, France

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