New hope for breast cancer patients with brain tumors: drug combo shows promise

NCT ID NCT05872347

First seen May 22, 2026 · Last updated May 22, 2026

Summary

This study tests a new drug called SPH4336 combined with hormone therapy for people with a type of breast cancer (HR-positive, HER2-negative) that has spread to the brain. The goal is to see if the combination can shrink or control brain tumors. About 52 adults with advanced disease who cannot have surgery will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Cancer Hospital, Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Anhui provincial hospital

    RECRUITING

    Hefei, Anhui, 230002, China

    Contact

  • Anyang Cancer Hospital

    RECRUITING

    Anyang, He'nan, 455001, China

    Contact

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, China

    Contact

  • Cancer Hospital of Xinjiang Medical University

    RECRUITING

    Ürümqi, Xinjiang, 830054, China

    Contact

  • Chongqing University Three Gorges Hospital

    RECRUITING

    Chongqing, 404031, China

    Contact

  • General Hospital of Ningxia Medical University

    RECRUITING

    Yinchuan, Ningxia, 750003, China

    Contact

  • Guangxi Medical University Cancer Hospital & Guangxi Cancer Institute

    RECRUITING

    Nanning, China

    Contact

  • Harbin Medical University cancer Hospital

    RECRUITING

    Harbin, Heilongjiang, 150081, China

    Contact

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, China

    Contact

  • Jiangsu Province Hospital

    RECRUITING

    Nanjing, Jiangsu, 210029, China

    Contact

  • Jilin Cancer Hospital

    RECRUITING

    Changchun, Jilin, 130012, China

    Contact

  • Liuzhou people's Hospital

    RECRUITING

    Liuzhou, Guangxi, 545026, China

    Contact

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, 100730, China

    Contact

  • The First Affiliated Hospital of Anhui Medical University

    RECRUITING

    Hefei, Anhui, 230022, China

    Contact

  • The First Affiliated Hospital of Bengbu Medical College

    RECRUITING

    Bengbu, China

    Contact

  • The First Affiliated Hospital of Henan University of Science and Technology

    RECRUITING

    Luoyang, He'nan, 450052, China

    Contact

  • The Fourth Hospital of Hebei Medical University

    RECRUITING

    Shijiazhuang, Hebei, 050011, China

    Contact

  • The first hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130061, China

    Contact

  • The second people's hospital of neijiang

    RECRUITING

    Neijiang, Sichuan, 641199, China

    Contact

  • Tianjin Medical University Cancer Institute & Hospital

    RECRUITING

    Tianjin, China

    Contact

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, China

    Contact

  • Xi'An International Medical Cancer Hospital

    RECRUITING

    Xi'an, China

    Contact

  • Xiangyang Central Hospital

    RECRUITING

    Xiangyang, Hubei, 441021, China

    Contact

  • Zhejiang cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310005, China

    Contact

Conditions

Explore the condition pages connected to this study.