New cancer drug SPGL008 enters first human tests

NCT ID NCT07038005

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new biologic drug called SPGL008 in 96 adults with advanced solid tumors that have spread or cannot be removed. The main goals are to find a safe dose and check for side effects. The drug is given either through a vein or under the skin. This is a Phase 1 study, so it is too early to know if the drug works against cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SPGL008 (a biologic drug)

What this could lead to

If safe and effective, SPGL008 could become a new treatment option for advanced cancers that have not responded to other therapies.

What could go wrong

This is a very early Phase 1 trial focused on safety and dosing, not on curing cancer. Many drugs fail at this stage, and side effects are unknown. Results may not apply to all cancer types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chongqing University Cancer Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, 400030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••