Leukemia drug spectrila tested in adults: phase 2 trial looks at drug levels and safety
NCT ID NCT03156790
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested the drug Spectrila (a form of L-asparaginase) in 40 adults aged 18-55 with newly diagnosed B-cell acute lymphoblastic leukemia. The goal was to see if the drug reached effective levels in the blood and to check its safety and immune response. The trial was terminated early, but Spectrila is already approved in Europe for first-line treatment of all ages.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Contacts and locations
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Locations
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Hospital Estadual Mario Covas
Santo André, 09190 615, Brazil
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Hospital Rio Grande Natal
Natal, 59020-100, Brazil
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Hospital das Clínicas São Paulo USP
Ribeirão Preto, 14048-900, Brazil
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Hospital das Clínicas da UFG
Goiânia, 74605-020, Brazil
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Hospital das Clínicas da Universidade Federal de Minas Gerais
Belo Horizonte, 30130-100, Brazil
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Hospital de Clínicas Porto Alegre
Pôrto Alegre, 90035-903, Brazil
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INCA Instituto Nacional do Cancer
Rio de Janeiro, 20231-048, Brazil
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Universidade Estadual de Campinas
Campinas, 13083-878, Brazil