New skin patch could ease acute back pain without pills
NCT ID NCT05096494
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study tests whether a medicated skin patch called SP-103 can reduce pain and disability in people with moderate to severe acute lower back pain. Participants wear the patch for 12 hours daily over 28 days. The trial compares the active patch to a placebo patch to see if it truly helps.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SP-103 topical system
- What this could lead to
- If it works, this could provide a new non-invasive treatment option for acute lower back pain without the need for oral painkillers.
- What could go wrong
- This is an early Phase 2 study with only 76 participants, so results may not apply to everyone. The patch may not provide significant pain relief compared to placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Arizona Research Center
Phoenix, Arizona, 85053, United States
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Chicago Anesthesia Research Specialists
Chicago, Illinois, 60657, United States
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Costal Clinical Research Specialists
Fernandina Beach, Florida, 32034, United States
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Costal Clinical Research Specialists
Jacksonville, Florida, 32250, United States
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Horizon Clinical Research
Newnan, Georgia, 30265, United States
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Injury Care Research
Boise, Idaho, 83704, United States
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Neuroscience Institute, Overlook Medical Center
Summit, New Jersey, 07901, United States
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Neuroscience Research Center
Overland Park, Kansas, 66210, United States
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Scilex Research Site 08
Charleston, South Carolina, 29406, United States
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Western Reserve Hospital
Cuyahoga Falls, Ohio, 44223, United States