New combo aims to control aggressive lymphoma – but not cure it

NCT ID NCT07029737

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tests a drug called acalabrutinib combined with standard chemotherapy (R-CHOP) in 55 adults with untreated mantle cell lymphoma who cannot have a stem cell transplant. The goal is to see how well the combination shrinks tumors and controls the disease. Participants will continue taking acalabrutinib indefinitely, so this approach aims to manage the cancer long-term rather than cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    A Coruña, 15006, Spain

  • Research Site

    RECRUITING

    Alcorcón, 28922, Spain

  • Research Site

    RECRUITING

    Badalona, 08916, Spain

  • Research Site

    RECRUITING

    Barcelona, 08035, Spain

  • Research Site

    RECRUITING

    Barcelona, 08036, Spain

  • Research Site

    RECRUITING

    Burgos, 09006, Spain

  • Research Site

    RECRUITING

    Donostia / San Sebastian, 20014, Spain

  • Research Site

    RECRUITING

    Gijón, 33206, Spain

  • Research Site

    RECRUITING

    Madrid, 28005, Spain

  • Research Site

    RECRUITING

    Madrid, 28006, Spain

  • Research Site

    RECRUITING

    Madrid, 28007, Spain

  • Research Site

    RECRUITING

    Madrid, 28029, Spain

  • Research Site

    WITHDRAWN

    Majadahonda, 28222, Spain

  • Research Site

    RECRUITING

    Málaga, 29010, Spain

  • Research Site

    RECRUITING

    Palma de Mallorca, 07198, Spain

  • Research Site

    RECRUITING

    Salamanca, 37007, Spain

  • Research Site

    RECRUITING

    Santa Cruz de Tenerife, 38010, Spain

  • Research Site

    RECRUITING

    Santander, 39008, Spain

  • Research Site

    RECRUITING

    Seville, 41013, Spain

  • Research Site

    RECRUITING

    Valencia, 46010, Spain

  • Research Site

    RECRUITING

    Valencia, 46017, Spain

  • Research Site

    RECRUITING

    Vigo, 36214, Spain

Conditions

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