New combo therapy aims to control rare blood cancer long-term

NCT ID NCT07029737

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 30 times

Summary

This study tests a drug called acalabrutinib combined with standard chemotherapy (R-CHOP) in people with untreated mantle cell lymphoma, a rare blood cancer. About 55 adults in Spain who cannot have a stem cell transplant will receive the combination for 6 cycles, then continue acalabrutinib alone plus maintenance rituximab. Treatment continues as long as it works and side effects are manageable, meaning this is a disease control approach, not a cure.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    A Coruña, 15006, Spain

  • Research Site

    RECRUITING

    Alcorcón, 28922, Spain

  • Research Site

    RECRUITING

    Badalona, 08916, Spain

  • Research Site

    RECRUITING

    Barcelona, 08035, Spain

  • Research Site

    RECRUITING

    Barcelona, 08036, Spain

  • Research Site

    RECRUITING

    Burgos, 09006, Spain

  • Research Site

    RECRUITING

    Donostia / San Sebastian, 20014, Spain

  • Research Site

    RECRUITING

    Gijón, 33206, Spain

  • Research Site

    RECRUITING

    Madrid, 28005, Spain

  • Research Site

    RECRUITING

    Madrid, 28006, Spain

  • Research Site

    RECRUITING

    Madrid, 28007, Spain

  • Research Site

    RECRUITING

    Madrid, 28029, Spain

  • Research Site

    WITHDRAWN

    Majadahonda, 28222, Spain

  • Research Site

    RECRUITING

    Málaga, 29010, Spain

  • Research Site

    RECRUITING

    Palma de Mallorca, 07198, Spain

  • Research Site

    RECRUITING

    Salamanca, 37007, Spain

  • Research Site

    RECRUITING

    Santa Cruz de Tenerife, 38010, Spain

  • Research Site

    RECRUITING

    Santander, 39008, Spain

  • Research Site

    RECRUITING

    Seville, 41013, Spain

  • Research Site

    RECRUITING

    Valencia, 46010, Spain

  • Research Site

    RECRUITING

    Valencia, 46017, Spain

  • Research Site

    RECRUITING

    Vigo, 36214, Spain

Conditions

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