Diabetes drug sotagliflozin tested as potential blood thinner

NCT ID NCT06933056

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-phase study at the University of Michigan will test whether the diabetes drug sotagliflozin can reduce platelet activity as well as FDA-approved antiplatelet drugs like aspirin, clopidogrel, and apixaban. Twenty healthy volunteers will take each drug for two weeks, and researchers will measure blood samples for clotting and platelet function. The goal is to see if sotagliflozin might have hidden benefits for heart health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sotagliflozin

What this could lead to

If sotagliflozin shows strong antiplatelet effects, it could point toward a new use for this diabetes drug in preventing blood clots.

What could go wrong

This is a very small, early-phase study in healthy volunteers, not patients. Results may not apply to real-world conditions, and the drug may not outperform existing options.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact