Two-Drug combo tested as new hope for Tough-to-Treat cancers

NCT ID NCT05256381

Summary

This study tested whether adding an experimental drug called SOT101 to an existing immunotherapy (pembrolizumab) could help control advanced cancers that had stopped responding to other treatments. It involved 166 adults with specific advanced solid tumors, including lung, colorectal, and ovarian cancers. The main goal was to see if the combination could shrink tumors and was safe for patients.

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Contacts and locations

Locations

  • Azienda Ospedaliera Universitaria Integrata Verona

    Verona, 37134, Italy

  • Azienda Ospedaliera Universitaria Senese - L'ospedale Santa Maria alle Scotte

    Siena, 53100, Italy

  • Azienda Socio Sanitaria Territoriale (ASST) degli Spedali Civili di Brescia

    Brescia, 25123, Italy

  • Centre Antoine Lacassagne

    Nice, 06189, France

  • Centre Francois Baclesser

    Caen, 14076, France

  • Centre Hospitalier Universitaire de Liège

    Liège, 4000, Belgium

  • Centre Hospitalier Universitaire de Nantes

    Nantes, 44093, France

  • Centre de Lutte Contre le Cancer

    Caen, 14076, France

  • Clinica Universidad de Navarra - Pamplona

    Madrid, 28027, Spain

  • Cliniques Universitaires Saint-Luc

    Brussels, 1200, Belgium

  • Clínica Universidad de Navarra - Madrid

    Madrid, 28027, Spain

  • Consilium Medulla Multiprofile Clinic

    Tbilisi, 0186, Georgia

  • Evex Hospitals - Caraps Medline

    Tbilisi, 0159, Georgia

  • Evex Hospitals - Caucasus Medical Center

    Tbilisi, 0186, Georgia

  • Evex Hospitals- Kutaisi Referral

    Kutaisi, 4600, Georgia

  • Fakultní nemocnice Olomouc

    Olomouc, 77900, Czechia

  • Fondazione Policlinico Universitario Agostino Gemelli

    Rome, 00168, Italy

  • Grand Hospital de Charleroi

    Charleroi, 6000, Belgium

  • Gustave Roussy

    Villejuif, 94805, France

  • High Technology Hospital MedCenter Ltd - Batumi

    Batumi, 6000, Georgia

  • Hospital Clínico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Germans Trias i Pujol

    Badalona, 08916, Spain

  • Hospital L'archet

    Nice, 06202, France

  • Hospital Teresa Herrera - Materno Infantil

    A Coruña, 15006, Spain

  • Hospital Universitari Vall d'Hebrón

    Barcelona, 08035, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario HM Sanchinarro

    Madrid, 28050, Spain

  • Hospital Universitario Puerta de Hierro - Majadahonda

    Madrid, 28222, Spain

  • Hospital del la Timone

    Marseille, 13005, France

  • Hôpital Ambroise-Paré

    Boulogne-Billancourt, 92100, France

  • Hôpital Foch

    Suresnes, 92150, France

  • Innovative Clinical Research Institute

    Whittier, California, 90603, United States

  • Institut Catala d'Oncologia

    Barcelona, 08908, Spain

  • Institut Jules Bordet

    Anderlecht, 1070, Belgium

  • Institut Universitaire du Cancer de Toulouse Oncopole

    Toulouse, 31059, France

  • Institute Claudius Regaud

    Toulouse, 31059, France

  • Instituto Nazionale Tumori IRCCS Fondazione G. Pascale

    Naples, 80131, Italy

  • Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST

    Meldola, 47014, Italy

  • Jerarsi Clinic

    Tbilisi, 0167, Georgia

  • LLC Todua Clinic

    Tbilisi, 0112, Georgia

  • MTZ Clinical Research powered by Pratia

    Warsaw, 02-172, Poland

  • Masarykuv Onkologicky Ustav

    Brno, 656 53, Czechia

  • Merchant Logo Institute Bergonié

    Bourdeaux, 33000, France

  • Nemocnice Hořovice

    Hořovice, 268 31, Czechia

  • New Vision University Hospital

    Tbilisi, 0159, Georgia

  • Ospedale Civile di Sondrio

    Sondrio, 23100, Italy

  • Ospedale Guglielmo da Saliceto

    Piacenza, 29121, Italy

  • Petz Aladár Egyetemi Oktató Kórház - Győr

    Győr, 9023, Hungary

  • Pratia Poznań

    Skorzewo, 60-185, Poland

  • Tbilisi Institute of Medicine

    Tbilisi, 0160, Georgia

  • Universitair Ziekenhuis Leuven - Campus Gasthuisberg

    Leuven, 3000, Belgium

  • University of Pittsburg Medical Center (UPMC) Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

  • Uniwersytecki Szpital Kliniczny w Poznaniu

    Poznan, Greater Poland Voivodeship, 60-780, Poland

  • Észak-Pesti Centrumkórház - Honvédkórház

    Budapest, 1134, Hungary

Conditions

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