Liver cancer drug shows promise in Late-Stage patients

NCT ID NCT05117957

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the drug sorafenib in 50 adults with advanced liver cancer that had worsened after at least one prior treatment. Participants took sorafenib daily to see if it could slow tumor growth and improve survival. The trial measured how long patients lived without their cancer getting worse and monitored side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sorafenib (a targeted cancer drug taken as a pill)

What this could lead to

If successful, this could provide a treatment option for patients with advanced liver cancer who have not responded to other therapies.

What could go wrong

This is a small, early-phase trial (50 participants) with no control group, so results may not be definitive. Sorafenib can cause side effects like fatigue, diarrhea, and skin reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Cancer Center, Korea

    Seoul, South Korea