New combo therapy targets Hard-to-Treat head and neck cancers

NCT ID NCT00494182

First seen Nov 10, 2025 · Last updated May 07, 2026 · Updated 22 times

Summary

This study tests whether adding the drug sorafenib to standard chemotherapy (carboplatin and paclitaxel) can help control advanced head and neck cancer that has spread or returned. About 48 adults with this type of cancer will receive the combination treatment. The goal is to see how well the tumors shrink or stop growing, and to track how long patients stay progression-free.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.