New drug combo aims to boost CAR-T success in hard-to-treat lymphoma
NCT ID NCT07341191
First seen Jan 16, 2026 · Last updated Jun 16, 2026 · Updated 25 times
Summary
This study tests whether adding two oral medications (sonrotoclax and zanubrutinib) to standard CAR-T cell therapy can improve treatment results for people with mantle cell lymphoma that has come back or not responded to prior treatment. About 40 adults who are already eligible for CAR-T therapy will take these drugs alongside their usual care. The goal is to see if this combination leads to better cancer control and longer survival.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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BCCA - Vancouver
NOT_YET_RECRUITINGVancouver, British Columbia, V5Z 4E6, Canada
Contact Phone: •••-•••-••••
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University Health Network
RECRUITINGToronto, Ontario, M5G 2M9, Canada
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