Single-Day light and sound therapy could replace surgery for common skin cancer
NCT ID NCT07381972
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests a new approach called sonophotodynamic therapy (Sono-PDT) for nodular basal cell carcinoma, a common skin cancer. The treatment combines a light-activated cream with sound waves in a single visit. Researchers will check if the tumor is gone after one month and if it stays away for six months. 142 adults with small skin cancers (≤1 cm) are being recruited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- methyl aminolevulinate (MAL) cream plus light and sound therapy
- What this could lead to
- If it works, this could offer a faster, single-visit treatment for common skin cancers, reducing the need for surgery.
- What could go wrong
- This is still an early-phase trial with only 142 participants. The treatment may not work for all types of skin cancer, and there is a risk of incomplete tumor clearance or recurrence.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NODULAR BASAL CELL CARCINOMA OF SKIN are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Amaral Carvalho
RECRUITINGJaú, São Paulo, 17210-080, Brazil