Single-Day light and sound therapy could replace surgery for common skin cancer

NCT ID NCT07381972

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests a new approach called sonophotodynamic therapy (Sono-PDT) for nodular basal cell carcinoma, a common skin cancer. The treatment combines a light-activated cream with sound waves in a single visit. Researchers will check if the tumor is gone after one month and if it stays away for six months. 142 adults with small skin cancers (≤1 cm) are being recruited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

methyl aminolevulinate (MAL) cream plus light and sound therapy

What this could lead to

If it works, this could offer a faster, single-visit treatment for common skin cancers, reducing the need for surgery.

What could go wrong

This is still an early-phase trial with only 142 participants. The treatment may not work for all types of skin cancer, and there is a risk of incomplete tumor clearance or recurrence.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nodular basal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Amaral Carvalho

    RECRUITING

    Jaú, São Paulo, 17210-080, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••