New hope for psoriatic arthritis sufferers: experimental drug sonelokimab enters final trial phase

NCT ID NCT06641089

Recruiting now Disease control Sponsor: MoonLake Immunotherapeutics AG Source: ClinicalTrials.gov ↗

First seen Nov 25, 2025 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tests a new drug called sonelokimab for adults with active psoriatic arthritis whose symptoms did not improve with standard TNF-blocker therapy. About 600 participants will receive either sonelokimab, a placebo, or an approved drug (risankizumab) for comparison. The main goal is to see if sonelokimab reduces joint swelling and pain by at least 50%.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Clinical SIte
RECRUITING

Gyula, 5700, Hungary
Clinical SIte
RECRUITING

Sabadell, 08208, Spain
Clinical Site
RECRUITING

Avondale, Arizona, 85392, United States
Clinical Site
COMPLETED

Chandler, Arizona, 85225, United States
Clinical Site
COMPLETED

Flagstaff, Arizona, 86001, United States
Clinical Site
RECRUITING

Mesa, Arizona, 85210, United States
Clinical Site
RECRUITING

Phoenix, Arizona, 85032, United States
Clinical Site
RECRUITING

Scottsdale, Arizona, 85260, United States
Clinical Site
RECRUITING

Tucson, Arizona, 85748, United States
Clinical Site
RECRUITING

Jonesboro, Arkansas, 72401, United States
Clinical Site
RECRUITING

La Jolla, California, 92037, United States
Clinical Site
RECRUITING

Pomona, California, 91767, United States
Clinical Site
RECRUITING

San Diego, California, 92108, United States
Clinical Site
RECRUITING

Santa Monica, California, 90404, United States
Clinical Site
RECRUITING

Thousand Oaks, California, 91360, United States
Clinical Site
RECRUITING

Upland, California, 91786, United States
Clinical Site
RECRUITING

Avon Park, Florida, 33825, United States
Clinical Site
RECRUITING

Clearwater, Florida, 33765, United States
Clinical Site
RECRUITING

Hialeah, Florida, 33016, United States
Clinical Site
RECRUITING

Miami Gardens, Florida, 33014, United States
Clinical Site
RECRUITING

Tampa, Florida, 33607, United States
Clinical Site
RECRUITING

Zephyrhills, Florida, 33542, United States
Clinical Site
RECRUITING

Gainesville, Georgia, 30501, United States
Clinical Site
RECRUITING

Springfield, Illinois, 62702, United States
Clinical Site
RECRUITING

Lake Charles, Louisiana, 70605, United States
Clinical Site
RECRUITING

Baltimore, Maryland, 21224-6821, United States
Clinical Site
RECRUITING

Grand Blanc, Michigan, 48439-2451, United States
Clinical Site
RECRUITING

Brooklyn, New York, 11201, United States
Clinical Site
RECRUITING

Rochester, New York, 14642, United States
Clinical Site
RECRUITING

Charlotte, North Carolina, 28262, United States
Clinical Site
RECRUITING

Leland, North Carolina, 28451, United States
Clinical Site
RECRUITING

Middleburg Heights, Ohio, 44130, United States
Clinical Site
RECRUITING

Portland, Oregon, 97239, United States
Clinical Site
RECRUITING

Duncansville, Pennsylvania, 16635, United States
Clinical Site
RECRUITING

Jackson, Tennessee, 38305, United States
Clinical Site
RECRUITING

Memphis, Tennessee, 38119, United States
Clinical Site
COMPLETED

Murfreesboro, Tennessee, 37128, United States
Clinical Site
RECRUITING

Allen, Texas, 75013, United States
Clinical Site
RECRUITING

Austin, Texas, 78745, United States
Clinical Site
RECRUITING

Baytown, Texas, 77521, United States
Clinical Site
RECRUITING

Colleyville, Texas, 76034, United States
Clinical Site
COMPLETED

Houston, Texas, 77089, United States
Clinical Site
RECRUITING

Lubbock, Texas, 79424, United States
Clinical Site
RECRUITING

Plano, Texas, 75024, United States
Clinical Site
RECRUITING

Seattle, Washington, 98122, United States
Clinical Site
RECRUITING

Beckley, West Virginia, 25801, United States
Clinical Site
RECRUITING

Pazardzhik, 4400, Bulgaria
Clinical Site
RECRUITING

Pleven, 5800, Bulgaria
Clinical Site
RECRUITING

Plovdiv, 4000, Bulgaria
Clinical Site
RECRUITING

Plovdiv, 4001, Bulgaria
Clinical Site
RECRUITING

Plovdiv, 4002, Bulgaria
Clinical Site
RECRUITING

Plovdiv, 4004, Bulgaria
Clinical Site
RECRUITING

Rousse, 7000, Bulgaria
Clinical Site
RECRUITING

Sofia, 1606, Bulgaria
Clinical Site
RECRUITING

Sofia, 1784, Bulgaria
Clinical Site
RECRUITING

Stara Zagora, 6003, Bulgaria
Clinical Site
RECRUITING

Toronto, Ontario, M5S1B2, Canada
Clinical Site
RECRUITING

Calgary, T2N 4L7, Canada
Clinical Site
RECRUITING

Trois-Rivières, G9A 3X2, Canada
Clinical Site
RECRUITING

Waterloo, N2J 1C4, Canada
Clinical Site
RECRUITING

Winnipeg, R3A IM3, Canada
Clinical Site
RECRUITING

Brno, 63800, Czechia
Clinical Site
RECRUITING

Ostrava, 70200, Czechia
Clinical Site
RECRUITING

Studénka, 742 13, Czechia
Clinical Site
RECRUITING

Zlín, 760 01, Czechia
Clinical Site
RECRUITING

Caluire-et-Cuire, 69300, France
Clinical Site
RECRUITING

Montpellier, 34295, France
Clinical Site
COMPLETED

Narbonne, 11100, France
Clinical Site
RECRUITING

Nice, 06001, France
Clinical Site
RECRUITING

Rouen, 76031, France
Clinical Site
RECRUITING

Tours, 37170, France
Clinical Site
RECRUITING

Tbilisi, 0102, Georgia
Clinical Site
RECRUITING

Tbilisi, 0112, Georgia
Clinical Site
RECRUITING

Tbilisi, 0141, Georgia
Clinical Site
RECRUITING

Tbilisi, 0159, Georgia
Clinical Site
RECRUITING

Tbilisi, 0179, Georgia
Clinical Site
RECRUITING

Tbilisi, 0180, Georgia
Clinical Site
RECRUITING

Berlin, 12161, Germany
Clinical Site
RECRUITING

Berlin, 12203, Germany
Clinical Site
RECRUITING

Berlin, 13125, Germany
Clinical Site
RECRUITING

Dresden, 01067, Germany
Clinical Site
RECRUITING

Erlangen, 91054, Germany
Clinical Site
RECRUITING

Hamburg, 20095, Germany
Clinical Site
RECRUITING

Herne, 44649, Germany
Clinical Site
RECRUITING

Munich, 80639, Germany
Clinical Site
RECRUITING

Munich, 81667, Germany
Clinical Site
RECRUITING

München, 80336, Germany
Clinical Site
RECRUITING

Budapest, 1027, Hungary
Clinical Site
RECRUITING

Budapest, 1036, Hungary
Clinical Site
COMPLETED

Budapest, 1036, Hungary
Clinical Site
RECRUITING

Debrecen, H-4032, Hungary
Clinical Site
RECRUITING

Hódmezővásárhely, 6800, Hungary
Clinical Site
RECRUITING

Nyíregyháza, 4400, Hungary
Clinical Site
RECRUITING

Székesfehérvár, 8000, Hungary
Clinical Site
RECRUITING

Szolnok, 5000, Hungary
Clinical Site
RECRUITING

Veszprém, 8200, Hungary
Clinical Site
RECRUITING

Bialystok, 15707, Poland
Clinical Site
RECRUITING

Bydgoszcz, 85-065, Poland
Clinical Site
RECRUITING

Częstochowa, 42-202, Poland
Clinical Site
RECRUITING

Elblag, 82-300, Poland
Clinical Site
RECRUITING

Gdynia, 81-384, Poland
Clinical Site
RECRUITING

Krakow, 30-002, Poland
Clinical Site
RECRUITING

Krakow, 30-149, Poland
Clinical Site
RECRUITING

Krakow, 31-501, Poland
Clinical Site
RECRUITING

Lodz, 91-363, Poland
Clinical Site
RECRUITING

Nadarzyn, 05-830, Poland
Clinical Site
RECRUITING

Poznan, 60-324, Poland
Clinical Site
RECRUITING

Poznan, 60-446, Poland
Clinical Site
RECRUITING

Poznan, 60-693, Poland
Clinical Site
RECRUITING

Poznan, 61-397, Poland
Clinical Site
RECRUITING

Sochaczew, 96-500, Poland
Clinical Site
RECRUITING

Swidnica, 58100, Poland
Clinical Site
RECRUITING

Warsaw, 00-874, Poland
Clinical Site
RECRUITING

Warsaw, 02-118, Poland
Clinical Site
RECRUITING

Warsaw, 02-665, Poland
Clinical Site
RECRUITING

Warsaw, 02-677, Poland
Clinical Site
RECRUITING

Warsaw, 03-291, Poland
Clinical Site
RECRUITING

Warsaw, 04-305, Poland
Clinical Site
RECRUITING

Wołomin, 05-200, Poland
Clinical Site
RECRUITING

Wroclaw, 51-685, Poland
Clinical Site
RECRUITING

Wroclaw, 53-673, Poland
Clinical Site
RECRUITING

A Coruña, 15006, Spain
Clinical Site
RECRUITING

Bilbao, 48013, Spain
Clinical Site
RECRUITING

Castellon, 12004, Spain
Clinical Site
RECRUITING

Madrid, 28003, Spain
Clinical Site
RECRUITING

Málaga, 29009, Spain
Clinical Site
RECRUITING

Santiago de Compostela, 15702, Spain
Clinical Site
RECRUITING

Santiago de Compostela, 15706, Spain
Clinical Site
RECRUITING

Seville, 41009, Spain
Clinical Site
RECRUITING

Seville, 41010, Spain
Clinical Site
RECRUITING

Seville, 41013, Spain
Clinical Site
RECRUITING

Valencia, 46010, Spain
Clinical Site
RECRUITING

Westcliff-on-Sea, Essex, SS0, United Kingdom
Clinical Site
RECRUITING

Barnet, EN5 3DJ, United Kingdom
Clinical Site
RECRUITING

Leeds, LS7 4SA, United Kingdom

Conditions

Explore the condition pages connected to this study.

ARTHRITIS, PSORIATIC