Can a simple drug stop dangerous leaks after pancreatic surgery?

NCT ID NCT03000946

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 35 times

Summary

This study tested whether somatostatin works better than octreotide at preventing pancreatic fistula, a common and serious leak after pancreatic surgery. Over 650 adults having their pancreas removed were randomly assigned to one of the two drugs. The goal was to see which drug reduces the risk of moderate-to-severe leaks.

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Contacts and locations

Locations

  • Cochin Hospital

    Paris, Paris, 75014, France

  • La Pitié Salpêtrière Hospital

    Paris, 75013, France

Conditions

The condition(s) this trial relates to.

Pancreatic Fistula

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.